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ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab PHASE2 The purpose of this study is to investigate the use of ctDNA measurements t...
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NYU Langone Health
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Signatera-Guided De-escalation of Adjuvant Therapy in Resectable Stage II-IVa Gastric/Gastric-Esophageal Cancer NA The goal of this clinical trial is to assess if circulating tumor DNA, as a...
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Multiple Locations
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CIPHER Study: Pilot Study to Study the Role of ctDNA in Triple Negative and HER2 Positive Early Stage EARLY_PHASE1 Primary Objective:
1\) To examine the impact of Circulating tumor DNA (ctD...
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Active Not Recruiting
Location
Trinitas Hospital and Comprehensive Cancer Center
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HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission PHASE2 Thie purpose of this study is to find out whether a personalized treatment ...
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Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
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Response Assessment by Circulating Tumor DNA in Patients With Locally Advanced Rectal Cancer N/A This is a single-arm observational study to determine the feasibility of as...
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Froedtert & the Medical College of Wisconsin
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Personalized Detection of ctDNA for Patients With HER2-Positive Metastatic Breast Cancer Patients Who Achieved Durable Response to Anti-HER2 Treatment N/A Anti-HER2 therapy, such as trastuzumab and pertuzumab, has significantly im...
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Active Not Recruiting
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A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy PHASE2 This study will look at the recurrence-free survival of microsatellite-stab...
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UF Health Davis Cancer Pavilion and Shands Med Plaza
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BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer N/A The BESPOKE CRC study will prospectively enroll patients who have undergone...
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Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests. PHASE2 Heroes is a multicentre, national, non-randomized, open-label, phase 2 stud...
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Centre Eugène marquis
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A Prospective Study Investigating the Relationship Between Minimal Residual Disease Detection, Monitoring Frequency, and Prognosis in Non-small Cell Lung Cancer Patients Eligible for Curative Treatment. N/A Adding immune checkpoint inhibitors or molecularly targeted drugs as adjuva...
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National Cancer Center Hospital
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