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A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE) PHASE2 The NSABP FC-13 study is being done to determine if using immunotherapies a...
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University of Florida
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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease PHASE2 This Phase II/III trial will evaluate the what kind of chemotherapy to reco...
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University of Alabama at Birmingham Cancer Center
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BESPOKE Study of ctDNA Guided Immunotherapy N/A This is a prospective data collection study of patients with advanced solid...
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ABCSG 61 / TEODOR : Neoadjuvant TrEatment Optimization Driven by Circulating Tumor DNA and endOcrine Responsiveness NA The goal of this performance study is to learn if treatment with neoadjuvan...
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Allg. Gynäkologie u. gyn. Onkologie/Senologie
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Observational Study of ctDNA in Resectable and Borderline Resectable Pancreatic Cancer N/A The purpose of this study is to collect information about treatment recomme...
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Inova Schar Cancer Institute
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A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors. NA This is a multicenter, open-label, randomized (1:1) trial designed to evalu...
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Multiple Locations
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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NA The purpose of this study is to evaluate the efficacy and safety of ctDNA-g...
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Mayo Clinic Arizona
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Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy N/A Blood samples will be tested to identify circulating tumor DNA and plasma p...
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Zhongshan Hospital Fudan University
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Predicting the Risk of Ovarian Cancer Recurrence Using Circulating Tumor DNA to Assess Residual Disease N/A Blood samples and Tumor tissue will be collected at certain timepoints and ...
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AHN West Penn Hospital
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ctDNA-Informed Management of Early-Stage Rectal Cancer PHASE2 This is a phase 2 pragmatic study to examine the utility of ctDNA-informed ...
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University of California Davis Comprehensive Cancer Center
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