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Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma PHASE2 Objectives:
Objectives
The primary objective of this study is to:
To ass...
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University of Texas MD Anderson Cancer Center
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Study to Assess Safety and Tolerability of MLN8237, In Combination With Erlotinib to Treat Non-Small Cell Lung Cancer PHASE1 This phase I/II trial studies the side effects and the best dose of MLN8237...
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Fox Chase Cancer Center
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Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas PHASE1 This phase I trial studies the side effects and best dose of alisertib and ...
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M D Anderson Cancer Center
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Alisertib (MLN8237) or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma PHASE3 This is a phase 3, randomized, 2-arm, open-label, international trial evalu...
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Multiple Locations
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A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas PHASE1 This phase I/Ib study is designed to establish the safety and maximum toler...
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City of Hope Comprehensive Cancer Center
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A Phase I Clinical and Pharmacodynamic Study of MLN8237, A Novel Aurora A Kinase Inhibitor, in Participants With Advanced Malignancies PHASE1 This is a multicenter, dose escalation, phase 1 study of MLN8237 in adult p...
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Ciutat Sanitaria Vall d'Hebron - Servicio de Oncologia
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A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma PHASE1 This study will assess the effect of multi-dose administration of itraconaz...
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Multiple Locations
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Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors PHASE1 This phase I trial studies the side effects and best dose of alisertib when...
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Smilow Cancer Center/Yale-New Haven Hospital
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Study of MLN8237 in Combination With Irinotecan and Temozolomide PHASE1 The goal of the first part of this clinical trial (Phase I portion) is to s...
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Children's Hospital Los Angeles
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Phase I Study of MLN0128 and MLN8237 in Patients With Advanced Solid Tumors and Metastatic Triple-negative Breast Cancer PHASE1 This is a phase Ib study designed to evaluate the safety and toxicity of th...
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University of Colorado Cancer Center
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