Found 56 matching trials
A Phase II Trial of LDK378 in ROS1 and /or ALK Over-expressed Advanced Intrahepatic or Hilar Cholangiocarcinoma
PHASE2Primary objective:
To investigate the objective response rate in patients ...
Location
National Taiwan University Hospital
LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.
PHASE2This was a single-arm, open-label, multicenter, phase II study to evaluate ...
Location
Novartis Investigative Site
An Open-label, Multicenter, Phase II Study of LDK378 in Patients With Non-small Cell Lung Cancer Harboring ROS1 Rearrangement
PHASE2ROS1 is a receptor tyrosine kinase with constitutive kinase activity. ROS1 ...
Location
Yonsei Cancer Center at Yonsei University Medical Center
A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer
PHASE2The purpose of this study was to evaluate the anti-tumor activity of single...
Location
Novartis Investigative Site
Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study
PHASE4The rollover study will provide ceritinib to patients who are currently rec...
Status
Active Not Recruiting
Location
Highlands Oncology Group
Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
PHASE4The purpose of this study is to observe the clinical effect and safety of R...
Location
Multiple Locations
Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer
PHASE2This National Cancer Institute (NCI)-NRG ALK Protocol phase II trial studie...
Location
CTCA at Western Regional Medical Center
Next Generation Personalized Neuroblastoma Therapy
PHASE1The purpose of this research study is to match genomic aberrations in tumor...
Location
The Children's Hospital of Philadelphia
Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Cancer
PHASE1This is an open label multi center trial to determine the safety and effica...
Status
Active Not Recruiting
Location
Mayo Clinic - Arizona
LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer
PHASE2A single-arm, open-label, two-stage multicenter, phase II study. Patients w...
Location
Massachusetts General Hospital Mass Gen 5