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Molecular Profiling of Advanced Soft-tissue Sarcomas PHASE3 MULTISARC is a randomized multicenter study assessing whether high throughp...
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Institut Bergonie
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Phase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung Cancer PHASE1 The primary purpose of the study is to estimate the maximum tolerated dose ...
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University of Colorado Dept. of Anschutz Cancer (3)
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LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib PHASE3 The primary purpose of the study was to compare the antitumor activity of L...
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Highlands Oncology Group
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LDK378 in Adult Chinese Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib PHASE1 A single-Arm, open-label, multi-center, phase I/II study in which the pharm...
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Novartis Investigative Site
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LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer PHASE3 To compare the efficacy and safety of ceritinib with standard first-line ch...
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Novartis Investigative Site
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Ceritinib in Mutation and Oncogene Directed Therapy in Thyroid Cancer PHASE2 This is an, open-label, protocol designed to evaluate the activity of targe...
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UT Southwestern Medical Center
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Study of Safety and Efficacy of LEE011 and Ceritinib in Patients With ALK-positive Non-small Cell Lung Cancer. PHASE1 This was a Phase Ib/II study of the ALK inhibitor ceritinib in combination ...
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Novartis Investigative Site
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Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation PHASE2 The purpose of this study is to assess the Treatment Strategies and Surviva...
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Pharmacokinetic and Safety Study of Lower Doses of Ceritinib Taken With a Low-fat Meal Versus 750 mg of Ceritinib in the Fasted State in Adult Patients With (ALK-positive) Metastatic Non-small Cell Lung Cancer (NSCLC) PHASE1 A Phase I study to assess the systemic exposure, effiacy, and safety of 450...
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Highlands Oncology Group
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A Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) Inhibitors N/A The primary purpose of this study is to determine the differences in PFS fo...
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