Found 19 matching trials
A Study of the Safety, Tolerability, and Bioavailability of Orally Administered Venglustat in Healthy Adult Participants PHASE1 The purpose of this study is to assess the effect of food on the bioavailab...
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Prism Research Site Number : 8400001
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A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2 PHASE3 Primary Objectives:
Primary population (adult participants with late-onset...
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Ataxia Center and HD Center of Excellence, 300 UCLA Med Plaza, Suite B200 - Investigational site number 8400004
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Study to Evaluate the Efficacy and Safety of Venglustat in Adult and Pediatric Patients With Gaucher Disease Type 3 PHASE3 This is a parallel arm, Phase 3, double-blind, double-dummy, active-compara...
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Active Not Recruiting
Location
Yale University School of Medicine - Investigational Site Number: 8400003
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Excretion Balance, Pharmacokinetics, and Metabolism Following of [14C]-Venglustat Administration in Healthy Male Subjects PHASE1 Primary Objectives:
* To determine the excretion balance and systemic expo...
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Investigational Site Number :8260001
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A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease PHASE3 This is a 12-month, parallel treatment, Phase 3, double-blind, randomized, ...
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Active Not Recruiting
Location
Nephrology Clinic at Kirklin Clinic of UAB Hospital_Investigational Site Number: 8400011
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A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of Genz-682452 in Healthy Volunteers PHASE1 To assess in healthy adult subjects:
* The tolerability and safety of asce...
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Multiple Locations
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Effect of Venglustat in Patients With Renal Impairment PHASE1 Primary Objective:
To study the effect of mild, moderate and severe renal ...
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Investigational Site Number 8400001
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Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension PHASE2 Part 1: Biomarker evaluation/screening phase
Primary Objectives:
* Evalua...
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Active Not Recruiting
Location
Yale University School of Medicine Site Number : 840002
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A Study of the Safety, Tolerability, and Bioequivalence of Orally Administered Venglustat in Healthy Adult Participants PHASE1 The purpose of this study is to assess the bioequivalent effect of venglust...
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Clinical Pharmacology of Miami Site Number : 8400001
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A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants PHASE1 The purpose of this study is to assess in healthy adult male participants t...
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