Found 72 matching trials
Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer PHASE2 This clinical trial is evaluating tucatinib in combination with Doxil in pa...
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Maryland Oncology Hematology
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A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer PHASE1 The purpose of this study is to determine the maximal tolerated dose (MTD) ...
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University of Alabama
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T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial PHASE3 This phase III trial compares the effect of usual treatment with trastuzuma...
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Active Not Recruiting
Location
University of Alabama at Birmingham Cancer Center
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Tucatinib+Trastuzumab+Eribulin in HER2+ MBC PHASE2 The purpose of this study is to evaluate the safety and efficacy of the thr...
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Active Not Recruiting
Location
University of Colorado
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A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib PHASE1 This study is being done to look at how tucatinib could affect the way othe...
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Covance Clinical Research Unit
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First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer PHASE1 OKI-219-101 is a Phase 1a/1b, open-label, multicenter, dose-escalation stud...
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Active Not Recruiting
Location
California Cancer Associates for Research and Excellence
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A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants PHASE1 This study will look at how a drug (tucatinib) leaves the body and what hap...
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Covance Clinical Research Unit
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Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer PHASE1 This research study will evaluate how well brain metastases associated with...
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Miami Cancer Institute at Baptist Health, Inc.
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Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy EARLY_PHASE1 The purpose of this study is to determine if the radiotracer, \[68Ga\]Ga-AB...
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Vanderbilt University Medical Center
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A Study of Tucatinib (MK-7119) in Combination With Trastuzumab and Capecitabine in Participants With Previously Treated Locally Advanced Unresectable or Metastatic Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Breast Carcinoma (MK-7119-001) PHASE2 The goal of this study is to evaluate the efficacy and safety of tucatinib ...
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Active Not Recruiting
Location
Aichi Cancer Center Hospital ( Site 1013)
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