Found 9 matching trials
A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC
PHASE2This study will evaluate the pharmacodynamic (PD), safety, antitumor activi...
An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer
PHASE2This Phase 2 Open-label Study examines the efficacy, safety, tolerability, ...
Location
Yale Cancer Center
Tomivosertib Combined With Pembrolizumab in Subjects With PD-L1 Positive NSCLC (KICKSTART)
PHASE2Tomivosertib combined with pembrolizumab in Subjects with PD-L1 positive NS...
Location
Southern Cancer Center
A Phase 1-2 Dose-Escalation and Cohort-Expansion Study of Oral Tomivosertib (eFT-508) in Subjects With Hematological Malignancies
PHASE1This clinical trial is a Phase 1-2, open-label, sequential-group, dose-esca...
Location
Samuel Oschin comprehensive Cancer Institute at Cedars-Sinai Medical Center
Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy
PHASE2Phase 2, open-label study that will evaluate the safety, tolerability, anti...
Location
University of Arizona - Cancer Center
A Dose Escalation and Cohort-Expansion Study of Oral eFT508 in Subjects With Advanced Solid Tumors
PHASE1This clinical trial is a Phase 1-2, open-label, sequential-group, dose-esca...
Location
SCRI at HealthONE
Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of Tomivosertib Combined With Paclitaxel in Advanced Breast Cancer
PHASE1This is a multicenter, open-label trial to evaluate the safety, pharmacodyn...
Location
Cross Cancer Institute
A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer
PHASE2This is a Phase 2, open-label, 2-part, multicenter study in subjects with M...
Tomivosertib in Relapsed or Refractory Acute Myeloid Leukemia (AML)
PHASE1Phase 1 of the study will open first with a (Bayesian optimal interval BOIN...
Location
Northwestern University