Found 121 matching trials
Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients PHASE3 Demonstrate an improvement in the composite scores of validated neurocognit...
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Sarah. S. Olelewe, MD
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Postoperative Tolvaptan Use in Left Ventricular Assist Device Implantation Patients N/A This research study will compare two standard of care approaches for managi...
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University of Chicago Medical Center
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Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites PHASE2 To observe the safety/efficacy of tolvaptan for treatment of patients with ...
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Renji hospital, Shanghai Jiaotong University School of Medicine
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Tolvaptan add-on Therapy to Overcome Loop Diuretic Resistance in Acute Heart Failure With Renal Dysfunction NA Renal dysfunction, which comprises 10%-40% of acute heart failure patients ...
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Cardiology Department
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A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure) PHASE2 This drug is being developed to treat cardiac edema. The primary purpose of...
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Otsuka Pharmaceutical Co., Ltd.
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Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure PHASE4 Broad Objectives: To determine the comparative efficacy of commonly employe...
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Vanderbilt University Medical Center
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The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study PHASE4 It is well known that the use of loop diuretics in acute setting may decrea...
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University of Michigan Health Systems
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A Study of HRS-9057 in Patients With Heart Failure and Volume Overload PHASE1 The study is an open-label, Tolvaptan-controlled Phase I study to evaluate ...
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The Second Affiliated Hospital of Guangzhou Medical University
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A Multicenter, Open-label, Dose-finding Trial of OPC-41061 to Investigate Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety in Patients With Carcinomatous Edema (Phase 2) PHASE2 OPC-41061 will be administered to patients with volume overload associated ...
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Multiple Locations
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A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Trial 156-04-251 in Japan] PHASE3 ADPKD patients who enrolled in Trial 156-04-251 will receive repeated oral ...
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Multiple Locations
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