Found 18 matching trials
CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma PHASE2 Tthe primary objective of this study is to compare blinded Independent Radi...
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University of Alabama at Birmingham
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Study to Evaluate the ECG Effects of Telaglenastat in Healthy Adult Subjects PHASE1 This study is designed to evaluate the effects of telaglenastat on cardiac ...
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Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer PHASE1 This phase Ib trial studies the side effects and best dose of telaglenastat...
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Active Not Recruiting
Location
University of Alabama at Birmingham Cancer Center
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Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects PHASE1 This study is designed to formally evaluate the impact of famotidine, an H2...
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Nucleus Network Brisbane Clinic (formerly Q-Pharm)
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KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC PHASE2 This is a Phase 2, randomized, multicenter, double-blind study of the gluta...
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University of Alabama at Birmingham
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TEPH: Telaglenastat Efficacy in Pulmonary Hypertension PHASE1 The research study is being conducted to evaluate the effectiveness of a dr...
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UPMC Presybeterian
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CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma PHASE1 This phase I trial studies the best dose of CB-839 HCl when given together ...
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Active Not Recruiting
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Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer PHASE1 This phase I/Ib trial studies the side effects and best dose of CB-839 HCl ...
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Active Not Recruiting
Location
City of Hope Comprehensive Cancer Center
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CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC) PHASE2 The primary objective of this study is to compare the progression-free surv...
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The University of Arizona Cancer Center
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Study of CB-839 in Combination w/ Paclitaxel in Participants of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC) PHASE2 CX-839-007 is an open-label Phase 2 study of the combination of CB-839 with...
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University of Alabama at Brimingham
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