Found 19 matching trials
A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)
PHASE2The primary objective of this trial is to evaluate the progress free surviv...
Location
Beijing Cancer Hospital
A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
PHASE1This is a Phase 1, open-label, first-in-human (FIH) dose-escalation study d...
Location
Honor Health (GIST, mastocytosis, other solid tumors)
A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib
PHASE2the primary objective of this study is to assess the efficacy (progression-...
Location
Beijing Cancer Hospital
A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST
PHASE1Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Subst...
Location
Mayo Clinic Florida
Expanded Access Program of Ripretinib (DCC-2618) for the Treatment of Patients With Advanced GIST
N/AThis is an open-label, single-arm, multicenter expanded access study to pro...
Status
Approved For Marketing
Location
Multiple Locations
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies
PHASE1This is a Phase 1/2, multicenter, open-label (unless otherwise specified in...
Location
University of Southern California - Norris Comprehensive Cancer Center
Ripretinib in Chinese Patients With Advanced GIST: a Real World Study
N/Ato evaluate the clinical efficacy, safety and predictive factors of ripetin...
Location
Beijing Cancer Hospital
Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy
NATo explore the efficacy and safety of preoperative treatment of potentially...
Location
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine
A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib
PHASE3This is a 2-arm, randomized, open-label, international, multicenter study c...
Status
Active Not Recruiting
Location
Mayo Clinic Scottsdale
Evaluate the Efficacy and Safety of Radiotherapy Combined With Ripretinib in the Treatment of Unresectable Advanced GIST
NAThe goal of this prospective study is to learn whether there is a synergist...
Location
The First Affiliated Hospital of Chongqing Medical University