Found 38 matching trials
Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine
PHASE1This study, is a Phase I/II clinical trial in three parts: Phase I Dose Esc...
Location
Banner MD Anderson Cancer Center
Efficacy and Safety of 5-day Dosing of ON 01910.Na in Intermediate-1,-2, or High Risk Myelodysplastic Syndrome (MDS)
PHASE1For MDS patients who have not responded to or have progressed after an init...
Location
Memorial Sloan-Kettering Cancer Center
Effect of 2-h Infusion of ON 01910.Na in Ovarian Cancer Patients
PHASE2ON 01910.Na has undergone preclinical and clinical phase I studies showing ...
Location
St. Vincent Gynecologic Oncology
Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin
PHASE1Treatment of cancer is often improved if two or more drugs are used in comb...
Location
Albert Einstein Cancer Center
Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA
PHASE3The study's primary objective \[in a population of patients with MDS after ...
Location
UC San Diego Moores Cancer Center
Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia
PHASE2The goal of this clinical research study is to learn if rigosertib can help...
Location
University of Texas MD Anderson Cancer Center
Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid Tumors
PHASE1Treatment of cancer is often more effective when two or more drugs are used...
Location
University of Colorado Cancer Center
Safety of ON 01910.Na as a 3-day Infusion in Patients With Advanced Cancer
PHASE1The primary objective of this study is to determine the largest dose of ON ...
Location
Mount Sinai School of Medicine
Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors
PHASE1Treatment of cancer is often more effective when two or more drugs are used...
Location
Department of Medicine, University of California San Francisco
Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AML
PHASE1The primary objective of this study is to evaluate the efficacy and safety ...
Location
Columbia University Medical Center