Found 9 matching trials
Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months
NAEfficacy Study of Gene Therapy for The Treatment of Acute Leber's Hereditar...
Location
Department of Ophthalmology ,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
A Phase 3, Multicenter, Randomized, Double-Masked, Sham-Controlled Clinical Trial for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation
PHASE3The objective of this clinical study is to evaluate the safety and efficacy...
Status
Active Not Recruiting
Location
Beijing Tongren Hospital, Capital Medical University
Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)
PHASE3The goal of this clinical trial is to assess the effectiveness of GS010, a ...
Location
Doheny Eye Center, University of California, Los Angeles
Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year
PHASE3The goal of this clinical trial is to assess the efficacy and safety of GS0...
Location
Doheny Eye Center UCLA Pasadena
A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy
PHASE2This study is meant to evaluate the safety and efficacy of rAAV2-ND4 treatm...
Location
Department of Ophthalmology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients
PHASE1The purpose of this study is to evaluate the safety and tolerability profil...
Location
CIC du CHNO DES QUINZE-VINGTS
RESCUE and REVERSE Long-term Follow-up
PHASE3The goal of this clinical trial is to assess the long-term safety and effic...
Location
Doheny Eye Center UCLA
Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)
NAThis study is meant to assess the safety and efficacy of rAAV2-ND4 treatmen...
Location
Department of Ophthalmology ,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation
PHASE3The goal of this clinical trial is to assess the effectiveness of GS010, a ...
Location
Doheny Eye Center, University of California, Los Angeles