Found 12 matching trials
Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy PHASE2 The purpose of this study is to establish a prospective, single-center plat...
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Fudan University Shanghai Cancer Center Shanghai, China, 200032
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Pyrotinib, Trastuzumab, Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer PHASE2 This study aims to evaluate the efficacy and safety of pyrotinib in combina...
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Active Not Recruiting
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine
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Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer PHASE2 Patients with Stage II-III HER2-positive breast cancer will receive three c...
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Shanghai Jiaotong University School of Medicine affiliated Ruijin Hospital
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Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer PHASE2 This prospective, response-guided phase II study investigates individualize...
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2nd Affiliated Hospital, School of Medicine, Zhejiang University
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Neoadjuvant Chemotherapy Plus Pyrotinib and Trastuzumab for HER2-positive Breast Cancer (NEOTORCH-BREAST05) PHASE2 This study is a prospective, single arm, multi-center clinical trial. The p...
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The First Affiliated Hospital, Zhejiang University School of Medicine
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Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer PHASE3 This is an open, prospective and interventional clinical study. Patients wi...
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The First Affiliated Hospital of Xi'an Jiaotong University
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Pyrotinib Versus Pertuzumab in Combination With Neoadjuvant Trastuzumab and Nab-Paclitaxel in HER2+ Early or Locally Advanced Breast Cancer PHASE2 The study is being conducted to evaluate the efficacy, and safety of pyroti...
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Multiple Locations
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Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer PHASE2 This study aims to evaluate the efficacy and safety of pyrotinib in combina...
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine
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A Multicenter Phase III Clinical Study and Translational Research on Adaptive Neoadjuvant Therapy of De-escalation and Escalation for HER2-Positive Breast Cancer Based on Multi-Omics Response Evaluation Model PHASE3 This study is a phase III clinical trial to explore the efficacy and safety...
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Multiple Locations
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This Study Aims to Optimize Neoadjuvant Therapy for HER2-positive Breast Cancer by Implementing a Dynamic Monitoring-guided Treatment Strategy. PHASE2 This study aims to optimize neoadjuvant therapy for HER2-positive breast ca...
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Multiple Locations
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