Found 49 matching trials
Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function
PHASE1This is a Phase 1, open-label, single-dose, sequential group study to compa...
Location
Advanced Pharma - Miami
Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam
PHASE1The purpose of this study is to determine the safety and tolerability of PA...
Location
MDS Pharma Services
Shortening Treatment by Advancing Novel Drugs
PHASE3The purpose of this study is to assess the efficacy, safety and tolerabilit...
Location
National Center for Tuberculosis and Lung Diseases
A Pan-TB Regimen Targeting Host and Microbe
PHASE2This project will develop the first regimen meeting WHO criteria for a pan-...
Status
Active Not Recruiting
Location
Instituto Nacional de Saúde
A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis
PHASE3This study aims to assess quabodepistat-based treatment regimens for RR/MDR...
Location
Capital Medical University - Beijing Chest Hospital
A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects.
PHASE1This study is a Phase 1, single-center, open-label, single-dose study to ev...
Location
Covance Clinical Research Unit
Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET
N/AThis is an observational study that will examine the pretomanid pharmacokin...
Location
Johns Hopkins Medical Institutions
Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
PHASE2The UNITE4TB consortium is a group of universities and pharmaceutical compa...
Location
PMSI Institute of Pneumology "Chiril Draganiuc"
Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid
PHASE1This is a single-dose, open-label, randomized, four-period, four-treatment,...
Location
Worldwide Clinical Trials Early Phase Services, LLC
Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)
PHASE2The trial will evaluate the extended bactericidal activity of 14 consecutiv...
Location
Centre for Tuberculosis Research Innovation, UCT Lung Institute