Found 9 matching trials
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib PHASE3 The purpose of this study is to evaluate the long-term safety and the clini...
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University of California LA
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A Drug-drug Interaction Study to Assess the Effect of Phenytoin and Itraconazole on the Pharmacokinetics of Pelabresib in Healthy Participants PHASE1 The purpose of this study is to assess the effect of multiple doses of phen...
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Multiple Locations
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Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis PHASE1 This Phase 1b, multicenter, open-label study aims to evaluate the safety, p...
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Novartis Investigative Site
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A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF) PHASE3 The purpose of this trial is to evaluate whether treatment with pelabresib ...
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Yale University School Of Medicine
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Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2) PHASE3 A Phase 3, randomized, blinded study comparing pelabresib (CPI-0610) and ru...
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Active Not Recruiting
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University of Alabama at Birmingham
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Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies PHASE1 Phase 1 2-part study to evaluate the effect of food on pharmacokinetics of ...
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Gabrail Cancer Center Research
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A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies PHASE1 Phase 1 Part: This was an open-label, sequential dose escalation study of p...
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Mayo Clinic Arizona
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Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment PHASE1 The primary purpose of this study is to evaluate the impact of hepatic func...
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Novartis Investigative Site
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A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies PHASE1 This drug-drug interaction (DDI) study aims to evaluate the impact of pelab...
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Novartis Investigative Site
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