Found 41 matching trials
Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients PHASE4 Study Synopsis Study Title: Double blind, single centre, cross-over study o...
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Multiple Locations
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Study to Evaluate the Efficacy and Safety of Sandostatin LAR at High Dose or in Combination Either With GH-receptor Antagonist or Dopamine-agonist in Acromegalic Patients PHASE4 This study will assess the efficacy of 8 months treatment of Sandostatin® L...
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Novartis Investigative Site
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A Relative Bioavailability Study To Evaluate Safety, Tolerability And Pharmacokinetic Comparability Of Pegvisomant 1 X 30 Mg Vs 2 X 15 Mg Subcutaneously Administered In Healthy Subjects PHASE1 The primary purpose of this study is to evaluate pharmacokinetic comparabil...
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Pfizer Investigational Site
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Effects of Pasireotide Lar Therapy on Bone Metabolism N/A Acromegaly, a chronic condition characterized by growth hormone (GH) and, i...
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS UOC Endocrinologia e Diabetologia
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Effect of Pegvisomant on GH/IGF-I Relationship in GHD NA Approximately 50% of middle-aged patients with severe AGHD have a normal ag...
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Christie Hospital NHS Trust
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Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance PHASE2 Background:
Lipodystrophy (LD) syndromes are a group of rare disorders tha...
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National Institutes of Health Clinical Center
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Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess PHASE3 Background:
For children with gigantism, too much growth hormone (GH) in t...
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National Institutes of Health Clinical Center
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Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients NA The purpose of this study is to investigate if co-treatment of acromegalic ...
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Department of Endocrinology, Aarhus University Hospital
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The RApid Switch From 1st Generation Somatostatin Analogues to PaSireOtiDe In Acromegaly N/A This is an observational, retrospective, national multicenter study aimed t...
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Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes PHASE2 Growth hormone is well known to cause changes in glucose regulation. People...
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San Francisco General Hospital
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