Found 35 matching trials
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
PHASE4Rib fractures cause a significant amount of pain and are associated with an...
Status
Enrolling By Invitation
Location
University of California, Irvine
A Study to Evaluate the Effect of Food on the Pharmacokinetics of VX-548
PHASE1The purpose of this study is to evaluate the pharmacokinetics (PK), safety,...
Location
ICON Salt Lake City
A Study Of Opioid Avoidance In Surgery Through Integrating Suzetrigine
PHASE4This prospective, single-arm feasibility study will evaluate postoperative ...
Location
Mayo Clinic in Florida
Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
PHASE3The purpose of this study is to evaluate the efficacy and safety of suzetri...
Location
Shoals Medical Trials Inc.
A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain
PHASE3The purpose of this study is to evaluate the safety and effectiveness of VX...
Location
Anaheim Clinical Trials
A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants
PHASE1The purpose of the study is to evaluate the effects of clinical and high cl...
Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment
PHASE1The purpose of this study is to evaluate the pharmacokinetics and safety of...
Location
Division of Clinical Pharmacology, University of Miami
A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin
PHASE1The purpose of this study is to evaluate the pharmacokinetics of midazolam ...
Location
Baltimore - Early Phase Clinical Unit
A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty
PHASE2The purpose of this study is to evaluate the efficacy and safety of VX-548 ...
Location
Arizona Research Center
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
PHASE4Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analge...
Location
University of California, Los Angeles (UCLA)