Trial Search

Current Search Criteria:

Intervention: neoadjuvant SCRT followed by Sintilimab plus CAPOX
Found 7 matching trials

A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer

PHASE2

The combination of short course radiotherapy and immunotherapy helps to inc...

Status

Completed

Location

Department of colorectal surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University

Start Date

2024-12-01

Trial ID

NCT06608537

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

PHASE2

The biological effective dose of short-course radiotherapy is relatively lo...

Status

Not Yet Recruiting

Location

Department of colorectal surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University

Start Date

2025-12-20

Trial ID

NCT07297030

Treatments Being Tested

Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial

PHASE3

This is a randomized, controlled clinical trial based on prior exploratory ...

Status

Not Yet Recruiting

Location

Guangdong Provincial People's Hospital

Start Date

2027-01-01

Trial ID

NCT07686796

Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

PHASE2

This study explores the key clinical issues in the field of neoadjuvant the...

Status

Recruiting

Location

Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College

Start Date

2025-06-01

Trial ID

NCT07040098

Short-Course Online Adaptive Radiotherapy Combined With Chemotherapy, Targeted Therapy and Immunotherapy as Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer

PHASE2

Standard treatment for patients with proficient mismatch repair (pMMR) / mi...

Status

Not Yet Recruiting

Location

China PLAGH

Start Date

2026-05-01

Trial ID

NCT07581626

Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer

PHASE2

This phase II/III trial studies how well neoadjuvant short-course radiother...

Status

Not Yet Recruiting

Location

Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College

Start Date

2022-08-06

Trial ID

NCT05484024

Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer-

PHASE2

This research investigates the efficacy and safety of combining Sintilimab,...

Status

Withdrawn

Location

Department of colorectal surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University

Start Date

2025-06-20

Trial ID

NCT06895577