Found 22 matching trials
Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs)
PHASE2This study will determine the safety and effectiveness of AMG 706 in patien...
Location
Multiple Locations
To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.
PHASE1The purpose of this study is to evaluate the safety, tolerability and pharm...
Location
Multiple Locations
Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors
PHASE1The study involves the use of three different dosing regimens of AMG 706 in...
Location
Multiple Locations
AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
PHASE2RATIONALE: AMG 706 may stop the growth of tumor cells by blocking some of t...
Location
Providence Saint Joseph Medical Center - Burbank
AMG 706 and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma
PHASE1RATIONALE: AMG 706 may stop the growth of cancer cells by blocking blood fl...
Location
Jonsson Comprehensive Cancer Center at UCLA
Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer
PHASE3This study will evaluate progression free survival (PFS), overall survival ...
Location
Multiple Locations
A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer
PHASE2The purpose of the study is to determine if AMG 706 will have clinically me...
Location
Multiple Locations
Impact of BRAFV600E Intratumor Heterogeneity in Thyroid Cancer Treated With Tyrosine Kinase Inhibitors
N/A* Background: BRAFV600E is the most frequent oncogene in differentiated thy...
Location
Department of Medicine and Surgery, Univeristy of Salerno
Safety of AMG 706 Plus Panitumumab Plus Chemotherapy in the Treatment of Subjects With Metastatic Colorectal Cancer
PHASE1The purpose of this study is to characterize the safety and tolerability of...
Location
Multiple Locations
Study Evaluating AMG 706 in Subjects With Advanced Solid Tumors
PHASE1This study will determine the safety and pharmacokinetics of AMG 706 in sub...
Location
Multiple Locations