Found 28 matching trials
Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors PHASE1 This is a 2-part Phase 1b study of BGB-283 (lifirafenib) and PD-0325901 (mi...
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University of California Los Angeles
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MEK Inhibitor PD-325901 To Treat Advanced Non-Small Cell Lung Cancer PHASE2 MEK is a critical member of the MAPK pathway involved in growth and surviva...
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Pfizer Investigational Site
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MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1 PHASE2 This phase II open label study will evaluate adolescents (≥ 16 years of age...
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Children's Hospital Los Angeles
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Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK PHASE1 This is a 3-part open-label study (feasibility phase, treatment phase and f...
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Alberta Children's Hospital
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A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma PHASE1 The purpose of this study is to find out whether mirdametinib in combinatio...
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Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
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SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma PHASE1 This is an open-label, multi-center, Phase 1/2 study of the brain-penetrant...
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St. Jude Children's Research Hospital
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A Study of Mirdametinib on Its Own or in Combination With Fulvestrant in People With Solid Tumor Cancer PHASE1 The purpose of this study to find out whether mirdametinib is a safe treatm...
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Memorial Sloan Kettering Monmouth (Limited protocol activities)
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Mirdametinib in Patients With Advanced NF1-mutant Melanoma PHASE2 The goal of this clinical trial is to evaluate clinical efficacy of mirdame...
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California Pacific Medical Center - Sutter Health
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A Single Patient IND for PD-0325901 N/A The purpose of this study is to provide access for a single patient to PD-0...
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No Longer Available
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Individual Patient Compassionate Use of Mirdametinib N/A This program is being offered on a patient by patient basis and will requir...
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Multiple Locations
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