Found 84 matching trials
Real-world Study of Local Therapy Changes During 1L Lorlatinib in Unresectable ALK+ NSCLC
N/AThis real-word study is designed to prospectively explore whether local tre...
Location
Multiple Locations
Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease
PHASE1This trial is testing two novel combinations (temozolomide plus osimertinib...
Location
University of Colorado Hospital
A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China
PHASE2A Phase 2, multi center, open label, dual cohort study to evaluate the effi...
Location
Gaoxin Hospital of The First Affilated Hospital of Anhui Medical University
Efficacy of Treatment Sequences in Patients With Non-small Cell Lung Cancer Receiving Lorlatinib
N/AThe study will evaluate progression-free survival, overall survival, best r...
Location
Aix-en-Provence - CH
Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India
PHASE4Lorlatinib is a third-generation, oral, reversible, ATP-competitive, macroc...
Location
The Gujarat Cancer and Research Institute
Iruplinalkib in ALK-Positive Advanced Lung Adenocarcinoma After Lorlatinib
N/AThis observational study aims to evaluate the real-world effectiveness and ...
Location
Peking University Shenzhen Hospital
The Patient-Reported Outcomes in ALK Positive Advanced NSCLC in China
N/AThis is a multicenter, prospective, longitudinal observational study design...
Location
Multiple Locations
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
EARLY_PHASE1The goal of this study is to determine the response of the study drug lorat...
Location
Children's Hospital Colorado
A Study To Evaluate The Effect Of Rifampin On Pharmacokinetics Of PF-06463922 In Healthy Volunteers
PHASE1The purpose of this study is to estimate the effect of rifampin on the sing...
Location
Pfizer New Haven Clinical Research Unit
A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer
PHASE1This study will test the safety of the combination of ramucirumab and lorla...
Status
Active Not Recruiting
Location
Memorial Sloan Kettering Monmouth (All Protocol Activities)