Found 20 matching trials
LOWER: Lomitapide Observational Worldwide Evaluation Registry N/A This global product exposure registry is a multicentre, long-term, prospect...
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Brookwood Baptist Medical Center
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Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in Hypercholesterolemia PHASE2 Evaluate the efficacy of combination therapy AEGR-733 plus atorvastatin 20 ...
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Linda Murray, DO - Radiant Research
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Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents PHASE2 This phase II, open-label research study was conducted in 129 healthy volun...
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University of Pennsylvania
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Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia N/A This observational, multicenter, retrospective and prospective study aims t...
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Active Not Recruiting
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CHRU Lille - Centre Hospitalier Universitaire de Lille
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Evaluate the Effect of Ethinyl Estradiol/Norgestimate on the Pharmacokinetics of Lomitapide in Healthy Female Subjects PHASE1 The primary objective of this study is to assess the effect of ethinyl estr...
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Covance Clinical Research Unit, Inc
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Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor PHASE2 The primary objective of this study is to evaluate the safety and tolerabil...
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University of Pennsylvania
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Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH) PHASE3 This is a single arm, open label, multi centre phase III study to evaluate ...
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Universtiats-Kinderlinik Heidelberg
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Effects of Lomitapide on Carotid and Aortic Atherosclerosis N/A Study to assess changes in carotid and aortic atherosclerosis in patients b...
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Multiple Locations
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A Comparative Bioavailability Study of Lomitapide 20 mg Intact vs Sprinkled PHASE1 To compare the relative bioavailability of lomitapide when administered by ...
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Richmond Pharmacology Ltd
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Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS PHASE2 To determine safety and effectiveness of low-dose therapeutic AEGR-733 +/- ...
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