Found 524 matching trials
Delayed Tolerance Through Mixed Chimerism PHASE1 This study will examine the safety and effectiveness of a bone marrow trans...
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Active Not Recruiting
Location
Massachusetts General Hospital
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Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) PHASE1 This is a Phase 1/2, open-label, multicenter study to determine the efficac...
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Active Not Recruiting
Location
Local Institution - 0006
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A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity PHASE2 This research study is studying the combination of anakinra and axicabtagen...
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Massachusetts General Hospital
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Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases PHASE1 The CATARSIS study explores the use of anti-CD19 CAR T-cell therapy as a no...
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Fondazione Policlinico Universitario A. Gemelli IRCCS
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Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations PHASE1 This phase I trial studies the side effects and best dose of autologous CD8...
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Fred Hutch/University of Washington Cancer Consortium
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Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer PHASE1 This phase I clinical trial evaluates the safety and feasibility of adminis...
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UCLA / Jonsson Comprehensive Cancer Center
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Vaccine Therapy in Treating Patients With Liver or Lung Metastases From Colorectal Cancer PHASE2 RATIONALE: Vaccines made from a gene-modified virus and a person's white bl...
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Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
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Immuno-virological Evaluation of Persons Living With HIV (PLWH) NA This is a dual arm (arm 1 and arm 2) multi-centric non-randomized (prospect...
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PD1 Integrated Anti-PSMA CART in Treating Patients With Castrate-Resistant Prostate Cancer PHASE1 PD1-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer...
Location
The First Affiliated Hospital, Zhejiang University
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Autologous Hematopoietic Stem Cell Transplantation for Neurological Damage Associated With Hereditary Homocysteine Remethylation Disorders NA This study aims to evaluate the safety, feasibility, and preliminary effica...
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Institute of Hematology & Blood Diseases Hospital, China
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