Found 14 matching trials
A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937) PHASE1 The purpose of this study is to evaluate the pharmacokinetics (PK) of a sin...
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CRS Clinical Research Services Kiel GmbH
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Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases PHASE2 The primary objective is to evaluate the intracranial efficacy of pemetrexe...
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Gachon University Gil Medical Center
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Lazertinib in Patients With NSCLC With Asymptomatic or Mild Symptomatic Brain Metastases After Failure of EGFR TKI. PHASE2 This is an open-label, single-intervention, multicenter clinical trial in p...
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Seoul National University Bundang Hospital
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A Study of Lazertinib in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC) PHASE1 The main purpose of this study is to evaluate the safety, tolerability, and...
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A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer PHASE3 The purpose of the study is to simplify amivantamab intravenous administrat...
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Active Not Recruiting
Location
City of Hope Duarte
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A Study of Lazertinib (JNJ-73841937) in Healthy Participants PHASE1 The purpose of this study is to evaluate the effect of steady-state concent...
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PRA Health Sciences
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Retrospective, External Comparator Study of Lazertinib as the 2nd-Line Treatment in Patients With EGFR Mutation+ NSCLC N/A This retrospective, external comparator study for Lazertinib aims to assess...
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Multiple Locations
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Clinical Trial to Assess Bioequivalence of Lazertinib Between Two Formulations in Healthy Volunteers. PHASE1 This Clinical Trial is an open, randomized, fasted, single-dose, oral admin...
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Seoul National University Hospital Clinical Trial Center
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Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer PHASE1 The purpose of study is to evaluate the safety, pharmacokinetics, and preli...
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Active Not Recruiting
Location
Multiple Locations
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Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301) PHASE3 This Phase III study will be conducted to evaluate the efficacy and safety ...
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Princess Alexandra Hospital
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