Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia
PHASE1
This phase Ib/II trial studies the best dose and safety of Bcl-2 inhibitor ...
Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
N/A
Background:
Bruton s tyrosine kinase inhibitors (BTKi) are used to treat a...
Status
Recruiting
Location
National Institutes of Health Clinical Center
Start Date
2023-03-01
Trial ID
NCT05724121
Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy
N/A
This study looks at how often atrial fibrillation (AF), an irregular heart ...
Status
Not Yet Recruiting
Location
City of Hope
Start Date
2026-08
Trial ID
NCT07711327
Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia
PHASE3
This phase III trial compares adding a new anti-cancer drug (venetoclax) to...
Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax
PHASE2
Phase 2, two cohort trial evaluating the addition of ublituximab and umbral...
A Real-world Study of Ibrutinib and Venetoclax (I+V) First-Line Treatment Given for Fixed-duration of Time in Participants With Chronic Lymphocytic Leukemia
N/A
The purpose of this study is to see how well Ibrutinib and Venetoclax (I+V)...