Found 28 matching trials
TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors PHASE2 The purpose of this study is to find out if removing a specific type of whi...
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Memorial SloanKettering Cancer Center
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Eltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA PHASE3 The analysis of our own clinical data suggests that majority of the hematol...
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Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
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A Study of Emapalumab for Pediatric Aplastic Anemia PHASE2 The purpose of this study is to find out whether upfront emapalumab treatme...
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
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Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases PHASE2 This study proposes the use of a reduced intensity chemotherapy/radiation t...
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Columbia University Medical Center
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UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic Anemia PHASE2 This Phase II open-label interventional clinical trial aims to evaluate the...
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University of Iowa Health Care
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Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma PHASE1 The purpose of this study is to examine the toxicity of using allogeneic st...
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University of Louisville
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Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic Anaemia PHASE2 To assess the tolerability and effectiveness of rabbit antithymocyte globul...
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Henri Mondor Hospital
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A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia PHASE2 This is a phase II, open label, multi-center, intra-patient dose escalation...
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Phoenix Childrens Hospital
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hATG+CsA vs hATG+CsA+Eltrombopag for SAA PHASE3 The null hypothesis of no difference in CR% at 3 months between the arms wi...
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Hopital Jean Minjoz
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Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation PHASE2 Background:
Blood stem cells in the bone marrow make all the cells to norm...
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Active Not Recruiting
Location
National Institutes of Health Clinical Center
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