Found 30 matching trials
CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia
PHASE2This is a phase 2 single-arm, open-label clinical trial determining efficac...
Status
Active Not Recruiting
Location
University of California, Los Angeles
Study To Determine The Effect Of Food And Strong CYP3A4 Enzyme Inhibitor On PF-04449913 Drug Levels
PHASE1The study aims to determine what effect a high fat meal will have on the dr...
Location
Pfizer Investigational Site
Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
PHASE1Glioblastomas (GBMs) are the most common malignant primary brain tumors. De...
Location
Institut Catalá de Oncología Badalona/Hospital Germans Trias i Pujol
Glasdegib Absolute Bioavailability Study
PHASE1This study is intended to estimate the absolute bioavailability of Glasdegi...
Location
New Haven Clinical Research Unit
A Phase 1 Study To Evaluate The Effect Of Glasdegib On The Cardiac Repolarization In Healthy Subjects
PHASE1This is a Thorough QT study intended to estimate the effect of glasdegib at...
Location
Pfizer Clinical Research Unit
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
PHASE3This is a multicenter, randomized, open-label, pragmatic low intervention c...
Location
University Hospital Brno
OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia
PHASE1This phase Ib/II trial studies the side effects and best dose of anti-OX40 ...
Location
M D Anderson Cancer Center
A Study Of PF-04449913 In Select Hematologic Malignancies
PHASE1This study examines the effect of a small molecule inhibitor to the Sonic H...
Location
UCSD Medical Center - La Jolla
A Study To Understand How Radiolabelled PF-04449913 Is Taken Up By The Body, Broken Down And Then Removed From The Body
PHASE1The study aims to understand, using radiolabelled PF-04449913, how this com...
Location
Pfizer Investigational Site
A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients
PHASE1This multi center open label Phase 1b study is designed to evaluate the saf...
Location
University of Alabama at Birmingham the Kirklin Clinic