Found 7 matching trials
A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function PHASE1 The goal of this phase 1 study is to assess the pharmacokinetics, safety an...
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Thomas C. Marbury
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A Drug-Drug Interaction Study of Denifanstat and Resmetirom in Healthy Adult Participants PHASE1 This is an open-label, 2-cohort study to evaluate the mutual DDI potential ...
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A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASLD and MASH PHASE3 A phase 3, randomized, double-blind, placebo-controlled study evaluating th...
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Multiple Locations
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TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer PHASE2 This phase II trial studies how well FASN inhibitor TVB-2640, paclitaxel, a...
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Mayo Clinic in Arizona
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A Study to Evaluate Safety of ASC40 Tablets in Patients With Moderate to Severe Acne Vulgaris PHASE3 This is a multicenter, open-label study designed to determine the long-term...
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Huashan Hospital Fudan University
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A Study to Evaluate the Safety and Efficacy of ASC40 (Denifanstat) Tablets in the Treatment of Patients With Moderate to Severe Acne Vulgaris PHASE3 This is a multicenter, randomized, double-blind, placebo-controlled Phase I...
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The First Affiliated Hospital of Bengbu Medical University
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A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis PHASE3 A randomized, double-blind, placebo-controlled Phase 3 study to determine i...
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Multiple Locations
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