Found 9 matching trials
Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)
PHASE1This is a phase I study designed to assess the maximum tolerated dose (MTD)...
Location
Montefiore Medical Center
SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)
PHASE1The objective of this study will be to evaluate the safety, tolerability an...
Location
Weill Cornell Medical Center/New York Presbyterian Hospital
Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR
PHASE1This study aims to investigate the pharmacokinetic/pharmacodynamic drug-dru...
Location
Seoul National University Bundang Hospital
Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression
PHASE3We investigate whether the add-on specific antitoxoplasmatic medication has...
Location
Multiple Locations
Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome
PHASE1This study will examine whether the drug pyrimethamine can shrink lymph nod...
Location
National Institute of Allergy and Infectious Diseases (NIAID)
Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma
EARLY_PHASE1NRF2 activation, observed in up to 40% of head and neck squamous cell carci...
Location
Washington University School of Medicine
LRAs United as a Novel Anti-HIV Strategy.
PHASE1A translational proof of concept study in humans on the primary research qu...
Pyrimethamine for the Treatment of Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
PHASE1In this research study we will start by looking for the highest dose of pyr...
Location
Beth Israel Deaconess Medical Center
Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy
PHASE3Background : When a mother contracts toxoplasmosis during pregnancy, the pa...
Location
Hôpital Louis Mourier