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Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali PHASE1 Background:
The disease malaria affects many people in Mali and other part...
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Malaria Research and Training Center
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Extended Duration Artemether-lumefantrine Treatment for Malaria in Children PHASE4 This project determines the pharmacokinetic/pharmacodynamic (PK/PD) of an e...
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Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials PHASE4 The purpose of the study is to evaluate the potential side-effects of artem...
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Jimma University Hospital
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Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo PHASE4 The Democratic Republic of the Congo (DRC) is among the countries most affe...
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Centre Evangélique de Coopération
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Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity PHASE4 This study specifically seeks to quantify the contribution of relapes to th...
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PNG Institute of Medical Research
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Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo PHASE4 This will be an open-randomised non-inferiority study to test the hypothesi...
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Multiple Locations
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Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria. PHASE2 KAE609 will be evaluated primarily for hepatic safety of single and multipl...
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Novartis Investigative Site
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Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon PHASE3 To assess the efficacy of artesunate-amodiaquine, dihydroartemisinin-pipera...
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L'Hopital de District Ngong, Garoua,
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In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria PHASE4 This study was designed to determine the efficacy of both artemether-lumefa...
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Malaria Alert Center, University of Malawi College of Medicine, Blantyre, Malawi
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Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children PHASE4 We will test the hypothesis that there is a difference in effectiveness of ...
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Mulago National Referral Hospital
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