Found 56 matching trials
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia NA This pilot clinical trial studies the feasibility of choosing treatment bas...
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Fred Hutch/University of Washington Cancer Consortium
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Novartis PhII Ceritinib (LDK378) in R/R ALK+ Hem Malignancies PHASE2 This is a phase II, single arm, unblinded study of ceritinib in patients wi...
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Duke University Medical Center
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Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell Lymphoma PHASE1 This phase I/II trial studies the side effects and best dose of ceritinib w...
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Fred Hutch/University of Washington Cancer Consortium
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Improving Public Cancer Care by Implementing Precision Medicine in Norway PHASE2 IMPRESS-Norway is a prospective, non-randomized clinical trial evaluating e...
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Sykehuset Ålesund
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Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis PHASE4 The purpose of this study is to observe the clinical effect and safety of R...
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Multiple Locations
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Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study PHASE4 The rollover study will provide ceritinib to patients who are currently rec...
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Active Not Recruiting
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Highlands Oncology Group
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A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1) PHASE1 Phase 1/2, dose escalation and expansion study designed to evaluate the saf...
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University of California Irvine Medical Center
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LDK378 in Adult Patients With ALK-activated NSCLC Previously Treated With Chemotherapy and Crizotinib PHASE2 A single-arm, open-label, multicenter, phase II study. Treatment with LDK37...
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Highlands Oncology Group Dept of Highlands Oncology Grp
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Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer PHASE2 This National Cancer Institute (NCI)-NRG ALK Protocol phase II trial studie...
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CTCA at Western Regional Medical Center
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Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis EARLY_PHASE1 This is two parallel studies to examine pharmacokinetic (PK), pharmacodynam...
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Barrow Brain and Spine
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