A Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Preoperative Brigatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Fusions.
PHASE2
This study is single arm, open label, phase II trial for resectable ALK+ NS...
Status
Unknown
Location
Yonsei University Health System, Severance Hospital
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
PHASE1
Phase 1/2, dose escalation and expansion study designed to evaluate the saf...
Retrospective, Observational, Multi-center Study Evaluating the Efficacy and Tolerance of Brigatinib in the Management of Rearranged CBNPC ROS1
N/A
ROS1 translocated Non small cell lung cancer (NSCLC) is a rare type of lung...
Status
Completed
Location
CHI Créteil
Start Date
2021-03-17
Trial ID
NCT04718012
Pulmonary Physiology and Systemic Inflammatory in EO Pulmonary Events With Brigatinib Use in NSCLC and Other Diseases
N/A
To estimate the incidence of Early Onset Pulmonary Events (EOPEs), defined ...
Status
Completed
Location
University of Colorado Denver
Start Date
2018-02-22
Trial ID
NCT03389399
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)
PHASE1
The purpose of this study is 2-fold: initially, in the dose escalation phas...