Found 17 matching trials
A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025)
PHASE2Researchers are looking for new ways to treat polycythemia vera (PV). Peopl...
Location
Multiple Locations
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
PHASE3The primary purpose of the study is to transition participants into an exte...
Location
University of Michigan ( Site 6000)
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
PHASE3The purpose of this study is to evaluate the efficacy and safety of bomedem...
Status
Active Not Recruiting
Location
Palo Verde Cancer Specialists ( Site 0052)
An Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms (IMG-7289-CTP-202/MK-3543-005)
PHASE2This is a multi-center, open-label extension study to assess the long-term ...
Location
University of Miami Leonard M. Miller
Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia
PHASE1This study aims to learn about the safety, tolerability, and different dose...
Location
University of Miami
Drug-Drug Interaction Study of Bomedemstat and Carbamazepine in Healthy Adult Participants (MK-3543-020)
PHASE1Researchers have designed a study medicine called bomedemstat (MK-3543) as ...
Location
Celerion, Inc. ( Site 0001)
A Study of Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023)
PHASE1The purpose of this study is to learn what happens to bomedemstat (MK-3543)...
Location
University of Miami ( Site 0003)
Bomedemstat (IMG-7289) Plus Ruxolitinib for Myelofibrosis
PHASE2This is an open-label, Phase 2 study of bomedemstat (IMG-7289), an inhibito...
Location
Department of Medicine, the University of Hong Kong, Queen Mary Hospital
A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)
PHASE1This is an open label study of the dose and duration of an orally administe...
Location
Royal Adelaide Hospital
Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)
PHASE1This is a Phase 1/2 open-label study to evaluate the safety, tolerability, ...
Location
University of Michigan