Found 14 matching trials
Factor Xa Inhibitor, PRT054021, Against Enoxaparin for the Prevention of Venous Thromboembolic Events (EXPERT)
PHASE2Randomized study of PRT054021 40 mg and 15 mg bid vs. enoxaparin 30 mg q12h...
Location
Montreal General Hospital
Study Evaluating Betrixaban in Pediatric Participants
PHASE1This trial was a Phase 1, open-label, multicenter study of the pharmacokine...
Location
Children's Hospital Los Angeles
Phase 2 Study of the Safety, Tolerability and Pilot Efficacy of Oral Factor Xa Inhibitor Betrixaban Compared to Warfarin
PHASE2Prevention of stroke in patients with atrial fibrillation (AF). Hypothesis:...
Location
Portola Investigational Site
A Human Phase I Absolute Bioavailability Study of PRT054021 in Healthy Male Volunteers
PHASE1This is a open label, single center, single oral dose, study of PRT054021, ...
Location
Multiple Locations
A Bioequivalence Study to Compare the Pharmacokinetics of Two Betrixaban Formulations
PHASE1This is a single center open label randomized 4-period 2-sequence replicate...
Location
Multiple Locations
A Healthy Volunteer PK/PD, Safety and Tolerability Study of Andexanet After Betrixaban Dosing
PHASE2This is a randomized, double-blind, single center study in healthy voluntee...
An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects
PHASE1This is a open label, single center, single oral dose, study of PRT054021, ...
Location
Multiple Locations
Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)
PHASE3The purpose of this study is to evaluate whether extended prophylaxis with ...
Location
Multiple Locations
The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist
PHASE1Single center, prospective open label PK and PD study of betrixaban in subj...
Location
Clinical Pharmacology of Miami
BRAVO - Betrixaban Registry Using Real Time Observations in Acute Medical Illness to Assess Venous Thrombosis and Bleeding Outcomes
N/APart 1 - Evaluate the real-world implementation of extended prophylaxis wit...