Found 125 matching trials
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer PHASE3 This is a global, randomized, double-blind, placebo-controlled, multicenter...
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Mayo Clinic Arizona
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An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation PHASE3 This is an international, multicenter, open-label, randomized, Phase 3 stud...
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Local Institution - 121
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Maintenance With Niraparib In Patients With Advanced Urothelial Cancer After 1st-line Platinum-based Chemotherapy PHASE2 This is a 2-arm, prospective, randomized (2:1 ratio), open-label, multi-cen...
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Azienda Sanitaria Locale CN2 - Alba e Bra
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Early Switch Maintenance vs Delayed Second-line Nivolumab in Advanced Stage Squamous Non-small Cell Lung Cancer (NSCLC) Patients (EDEN Trial) PHASE3 The study's hypothesis is that using Nivolumab as early switch maintenance,...
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UOC Oncologia - Azienda USL di Imola - Ospedale Santa Maria della Scaletta
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Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment PHASE3 The purpose of this study is to evaluate the efficacy and safety of oral ma...
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Centre Hospitalier Universitaire d'Amiens
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A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia PHASE2 The purpose of the study is to evaluate the efficacy and safety of luspater...
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Local Institution - 0008
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Masitinib for the Treatment of Severe Mast Cell Activation Syndrome PHASE2 To evaluate the efficacy and safety of two dosing schemes of oral masitinib...
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St Charles Clinical Research
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Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1) PHASE3 The objective of this Phase III study is to evaluate the efficacy of ninted...
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1199.52.0108 Boehringer Ingelheim Investigational Site
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Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts PHASE3 The primary objective of this study is to compare overall survival (OS) in ...
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Virginia G. Piper Cancer Center
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BIBW 2992 and BSC Versus Placebo and BSC in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib (LUX-LUNG 1) PHASE3 This randomized, double-blind, multi-center Phase IIb/III trial will be per...
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1200.23.038 Boehringer Ingelheim Investigational Site
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