Found 30 matching trials
A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling PHASE1 This is a Phase 1/2, multicenter, open-label trial of avapritinib in partic...
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Phoenix Children's Hospital
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(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis PHASE2 This is a Phase 2, randomized, double-blind, placebo-controlled study compa...
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Active Not Recruiting
Location
University of Alabama at Birmingham
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Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma PHASE1 This is a feasibility study in patients with localized or metastatic soft t...
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Monter Cancer Center (Northwell Health)
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Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM N/A BLU-285-2405 is a multi-center, synthetic control, observational and retros...
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Standford Cancer Center
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Early Access Program (EAP) for Avapritinib in Patients With Locally Advanced Unresectable or Metastatic GIST N/A This is a US, multicenter, open-label expanded access program to provide ac...
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Approved For Marketing
Location
Multiple Locations
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Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML PHASE2 The goal of this clinical trial is to estimate the rate (probability) of co...
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First Affiliated Hospital Of University of Science and Technology of China
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A Drug-drug Interaction Study of Avapritinib and Midazolam PHASE1 The purpose of this study is to investigate the effect of multiple dosing o...
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Mayo Clinic Florida
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(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies PHASE1 This is a Phase 1, open-label, dose-escalation study designed to evaluate t...
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Stanford Cancer Institute
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Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World N/A This study is an observational, multicenter, Real-word study to evaluate th...
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Beijing Cancer Hospital
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(NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors PHASE1 This is a Phase 1, open-label, first-in-human (FIH) study designed to evalu...
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Scottsdale Healthcare Hospitals DBA HonorHealth
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