🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

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🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: anti-PD-1 monoclonal antibody in combination with platinum and pemetrexed

Found 18 matching trials

BGB-15025 Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Participants With Advanced Solid Tumors

PHASE1

The primary objective of this study is to assess the safety and tolerabilit...

Status

Completed

Location

Icahn School of Medicine At Mount Sinai

Start Date

2021-03-04

Trial ID

NCT04649385

Treatments Being Tested

BGB-15025 Tislelizumab Carboplatin Cisplatin Pemetrexed Oxaliplatin Capecitabine Paclitaxel nab-paclitaxel

A Phase 3 Study of IN10018 in Combination With D-1553 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation

PHASE3

This is a multicenter, randomized, open-label, phase III clinical study, to...

Status

Recruiting

Location

Beijing Cancer Hospital

Start Date

2025-09-10

Trial ID

NCT07174908

Treatments Being Tested

IN10018 in combination with D-1553 anti-PD-1 monoclonal antibody in combination with platinum and pemetrexed

Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042

PHASE1

Part A: To test the safety and tolerability of combination therapy with Nir...

Status

Completed

Location

GSK Investigational Site

Start Date

2017-10-12

Trial ID

NCT03307785

Treatments Being Tested

Niraparib TSR-042 Carboplatin-Paclitaxel Bevacizumab TSR-022 Carboplatin-Pemetrexed Carboplatin-Nab-Paclitaxel

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

PHASE1

The purpose of this study is to learn about the safety and effects of the s...

Status

Terminated

Location

Highlands Oncology Group

Start Date

2024-12-10

Trial ID

NCT06704724

Treatments Being Tested

PF-07985045 Gemcitabine Nab-paclitaxel Cetuximab Fluorouracil Oxaliplatin Leucovorin Bevacizumab Pembrolizumab Sasanlimab pemetrexed Cisplatin Paclitaxel Carboplatin PF-07284892

Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer

PHASE2

This is a Phase II, open-label, 4-cohort study of the monoclonal antibody B...

Status

Completed

Location

Cancer Hospital Chinese Academy of Medical Sciences

Start Date

2017-08-24

Trial ID

NCT03432598

Treatments Being Tested

Tislelizumab Paclitaxel Gemcitabine Etoposide Pemetrexed Cisplatin Carboplatin

Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer

PHASE2

Determine anti-tumor efficacy by characterizing response rates on positron ...

Status

Recruiting

Location

Montefiore Einstein Comprehensive Cancer Center (MECCC)

Start Date

2025-08-07

Trial ID

NCT06865339

Treatments Being Tested

Cemiplimab Fianlimab Radiotherapy Platinum Doublet Chemotherapy (PDC)

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

PHASE1

The purpose of this study is to learn about the safety and effects of the s...

Status

Active Not Recruiting

Location

Highlands Oncology Group, PA

Start Date

2024-06-27

Trial ID

NCT06447662

Treatments Being Tested

PF-07934040 Gemcitabine Nab-paclitaxel Cetuximab Fluorouracil Oxaliplatin Leucovorin Bevacizumab Pembrolizumab pemetrexed Cisplatin Paclitaxel Carboplatin Sasanlimab

Effect of Neoadjuvant Anti-PD-1 Immunotherapy on Perioperative Analgesia and Postoperative Delirium

N/A

To observe the effect of preoperative anti-PD-1 monotherapy combined with c...

Status

Completed

Location

Tianjin Medical University Cancer Institute and Hospital

Start Date

2022-03-22

Trial ID

NCT05273827

Treatments Being Tested

neoadjuvant immunotherapy Neoadjuvant chemotherapy

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC

PHASE3

This is a randomized, multicenter, double-blind placebo-controlled phase 3 ...

Status

Unknown

Location

Regional Hospital Liberec

Start Date

2019-06-01

Trial ID

NCT03912389

Treatments Being Tested

BCD-100 Pemetrexed Cisplatin (or carboplatin)Placebo

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

PHASE2

This is a phase 2 study to evaluate zimberelimab (AB122) combined with domv...

Status

Active Not Recruiting

Location

Research Site

Start Date

2021-02-08

Trial ID

NCT04736173

Treatments Being Tested

Domvanalimab Zimberelimab Carboplatin Paclitaxel Pemetrexed Pembrolizumab

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