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Intervention: aliskiren 300 mg once daily

Found 39 matching trials

Efficacy and Safety of Aliskiren/Ramipril/Amlodipine Compared With Ramipril/Amlodipine and Aliskiren/Amlodipine in Patients With Metabolic Syndrome

PHASE4

This proof of concept study is designed to evaluate the efficacy and safety...

Status

Terminated

Location

Addenbrookes Hospital

Start Date

2008-03

Trial ID

NCT00542269

Treatments Being Tested

Amlodipine Aliskiren Ramipril

Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure

PHASE2

In addition to the blood pressure lowering effects of aliskiren, it may hav...

Status

Completed

Location

Novartis Investigator Site

Start Date

2009-05

Trial ID

NCT00923156

Treatments Being Tested

aliskiren ramipril Placebo to aliskiren Placebo to ramipril

A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus

PHASE4

The study objective was to assess the effect of single and multiple doses o...

Status

Completed

Location

Novartis Investigator Site

Start Date

2008-04

Trial ID

NCT00660309

Treatments Being Tested

Aliskiren Irbesartan Captopril

Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With Hypertension

PHASE4

The goal of this project is to evaluate the chronic effect (8 weeks) of RAS...

Status

Completed

Location

Centre Hospitalier Universitaire Vaudois

Start Date

2011-10

Trial ID

NCT01519635

Treatments Being Tested

Aliskiren Hydrochlorothiazide

Effects of Aliskiren and Amlodipine on the Renin-Angiotensin System (RAS) and Lipid/Carbohydrate Metabolism in Obese Patients With Hypertension

PHASE2

Part 1 determined: aliskiren, amlodipine and angiotensin II concentrations ...

Status

Terminated

Location

Novartis Investigative Site

Start Date

2007-06

Trial ID

NCT00498433

Treatments Being Tested

Aliskiren Amlodipine Placebo of Aliskiren Placebo of amlodipine

Efficacy and Safety of Aliskiren in Patients With Mild to Moderate Hypertension During Exercise

PHASE2

This study compared the blunting effect of aliskiren and valsartan monother...

Status

Completed

Location

Investigative Site

Start Date

2009-02

Trial ID

NCT00819767

Treatments Being Tested

Aliskiren Valsartan Placebo to aliskiren Placebo to valsartan

To Study the Effects of Aliskiren on Albuminuria and Various Biomarkers in Patients With Nephropathy

PHASE2

The study is designed to primarily assess the effect of aliskiren on albumi...

Status

Terminated

Location

Novartis Investigative Site

Start Date

2011-01

Trial ID

NCT01302899

Treatments Being Tested

Aliskiren Placebo to Aliskiren Hydrochlorothiazide (HCTZ)Placebo to Hydrochlorothiazide (HCTZ)Ramipril

The Effect of Renin Inhibition on Nerve Function in Diabetes

This study will assess the effect of direct renin inhibition on nerve funct...

Status

Completed

Location

Christiana Care Health Services

Start Date

2009-06

Trial ID

NCT00935064

Treatments Being Tested

Aliskiren Placebo

Effect of the Direct Renin Inhibitor Aliskiren on Endothelial Function and Arterial Stiffness in Diabetic Subjects

PHASE4

The study will evaluate the effects of the direct renin inhibitor, aliskire...

Status

Terminated

Location

UAB

Start Date

2011-06

Trial ID

NCT01349114

Treatments Being Tested

aliskiren 300 mg once daily Placebo/sugar pill

Direct Renin Inhibition Effects on Atherosclerotic Biomarkers

PHASE4

The investigators aim to assess if a new blood pressure medication, aliskir...

Status

Completed

Location

Texas Tech University Health Sciences Center

Start Date

2008-01

Trial ID

NCT00818779

Treatments Being Tested

Aliskiren Amlodipine

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