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A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC) PHASE2 This trial will evaluate the efficacy and safety of various therapies in pa...
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City of Hope Comprehensive Cancer Center
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Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study PHASE2 TAPISTRY is a Phase II, global, multicenter, open-label, multi-cohort study...
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Active Not Recruiting
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Western Regional Medical Center at Cancer Treatment Centers of America
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Monitoring Alectinib Treatment by Detection of ALK Translocations in Serial Blood Samples From Non-Small Cell Lung Cancer Patients N/A Circulating tumor DNA can be used to monitor the treatment effect and ident...
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Aarhus University Hospital
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A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib Treatment PHASE1 This open-label, non-randomized, multicenter, Phase 1/2 study will evaluate...
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University of Alabama at Birmingham
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The Food-effect on Alectinib Pharmacokinetics NA The goal of this food-effect study on Alectinib pharmacokinetics is to lear...
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Netherlands Cancer Institute
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ALK Inhibitor in Metastatic Colorectal Cancer With ALK Mutation. NA This clinical trial aims to evaluate the efficacy, safety of ALK inhibitor ...
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Shanghai Changzheng Hospital
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Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis PHASE4 The purpose of this study is to observe the clinical effect and safety of R...
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Multiple Locations
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A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802 PHASE1 This single center, open-label, 3-period, fixed-sequence study will evaluat...
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Multiple Locations
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A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site PHASE2 This study will compare the efficacy and safety of molecularly-guided thera...
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Blacktown Hospital
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A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC) PHASE3 The objective of this study is to explore the safety of alectinib in combin...
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Royal North Shore Hospital
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