Found 171 matching trials
Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD) PHASE2 The purpose of this study is to evaluate the the safety and efficacy of the...
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Research Center 1
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A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease PHASE1 The purpose of this study is to evaluate the safety and tolerability of sin...
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Clinical Trial Site
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Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor) PHASE4 The purpose of this study is to evaluate the effects of weekly augmentation...
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Multiple Locations
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Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency PHASE4 The goal of this study is to learn whether patients who have a genetic muta...
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University of Alabama at Birmingham
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Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection PHASE3 This is a Randomized, Open-Label Study of the Efficacy and Safety of Aralas...
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Blessing Corporate Services, Inc
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Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation" PHASE3 The goal of this clinical trial is to learn if AAT for inhalation, at a dos...
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University Hospital (UZ) Leuven
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Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD) EARLY_PHASE1 This is a single-arm, open-label, single-dose, dose-escalation exploratory ...
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Active Not Recruiting
Location
Ren Ji Hospital Affiliated to Shanghai Jiao Tong University
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Pharmacokinetic Study of ARALAST (Human Alpha1- PI) PHASE1 The primary purpose of this study is to characterize the pharmacokinetic pr...
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Multiple Locations
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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis) PHASE3 The liver produces a protein called alpha-1 antitrypsin (AAT). AAT is norma...
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St Joseph's Hospital and Medical Center
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International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema PHASE2 This is a randomised , placebo controlled, double blind , multicentre, Phas...
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Inspiration Research Limited
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