Found 90 matching trials
Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders
PHASE1This phase 1-2 trial studies the side effects and how well tipifarnib works...
Location
Stanford Cancer Institute
Study Assessing Efficacy of ZARNESTRA™ Combined With Tamoxifen in Patients With Advanced or Metastatic Breast Cancer
PHASE2The purpose of this study is to evaluate the objective response rate when Z...
Location
Institut Bergonie
Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies
PHASE1A Phase I, open-label clinical pharmacology study designed to evaluate the ...
Location
Gabrail Cancer Center Research
Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy
PHASE2Phase II study designed to investigate antitumor activity in terms of objec...
Location
Stanford University Medical Center
Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme
PHASE1The goal of this clinical research study is to find the highest safe dose o...
Location
MD Anderson Cancer Center
Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia
PHASE2A Phase 2 study to investigate the antitumor activity in terms of overall r...
Location
Mayo Clinic Arizona
Efficacy and Safety of the Farnesyl-transferase Inhibitor (Tipifarnib) in Mantle Cell Lymphoma
PHASE2To determine the EFFICACY and the SAFETY PROFILE and TOXICITY of Zarnestra®...
Location
Multiple Locations
Study of Letrozole Plus Tipifarnib or Placebo in the Treatment of Advanced Breast Cancer
PHASE2The purpose of this study is to determine if the addition of tipifarnib to ...
Location
Multiple Locations
Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery
PHASE2This randomized phase II trial is studying how well giving sorafenib togeth...
Location
University of Arkansas for Medical Sciences
S9923 R115777 in Treating Patients With Advanced Colorectal Cancer
PHASE2RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cell...
Location
USC/Norris Comprehensive Cancer Center