Found 10 matching trials
ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast Cancer
PHASE1The purpose of this research study is to determine the safety and tolerabil...
Location
Dana-Farber Cancer Institute
Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination
PHASE1A Phase I open label study to asses the safety and tolerability of ZD6474 i...
Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD)
PHASE1This multi-centre, non-randomized open phase I/randomized phase II study wi...
ZD6474 Phase IIa Dose Finding Multicentre Study
PHASE2To assess the objective response rates (by RECIST) to ZD6474 100, 200 and 3...
A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery
PHASE1The purpose of the study is to determine the most tolerable and safe dose o...
Location
Fox Chase Cancer Center
Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer
PHASE2At this point in the treatment of extensive stage SCLC, we have reached a p...
Location
Helen F. Graham Cancer Center
ZD6474(Vandetanib) + Alimta Combo Study
PHASE1The main purpose of this trial is to look to see if adding ZD6474 (100 mg o...
Location
Multiple Locations
Dose Escalation Study With Zactima and Chemotherapy in Metastatic Pancreas Carcinoma
PHASE1The purpose of this study is to define th Maximum Tolerated Dose (MTD) and ...
Phase I Chinese PK
PHASE1An open, phase 1 to assess the PK of rising doses of ZD6474 when administer...
Phase I Efficacy On Vascular Permeability In Patients With Advanced Colorectal Cancer
PHASE1A Phase I, Open-Label Study To Assess The Effect of ZD6474 (ZACTIMA) On Vas...