Found 25 matching trials
A Study Evaluating Safety and Tolerability of YM150 Compared to Warfarin in Subjects With Atrial Fibrillation PHASE2 The purpose of this study is to investigate the optimal daily dose and dose...
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Study Evaluating Safety, Tolerability and Efficacy of YM150 in Subjects With Acute Coronary Syndromes PHASE2 The purpose of this study is to evaluate the safety and efficacy of various...
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Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2) PHASE2 The purpose of this study is to find the best possible (optimal) dose (effe...
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Factor Xa Inhibitor for Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement PHASE2 Evaluate the safety and tolerability of escalating oral doses of YM150 in p...
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Prevention of Venous Thromboembolism in Subjects Undergoing Hip Fracture Surgery or Surgery in the Lower Extremities PHASE3 The study objective is to evaluate the efficacy and safety of oral YM150 fo...
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A Study to Evaluate the Safety and Efficacy of YM150 in Patients With Knee Replacement Surgery PHASE2 To evaluate the safety and efficacy of twice daily dosing and once daily do...
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A Pharmacokinetic Study to Investigate the Effect of Food on the Pharmacokinetics of YM150 Tablet PHASE1 This study is to evaluate the effect of food on the pharmacokinetics of YM1...
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A Study to Evaluate the Safety and Tolerability of YM150 in Healthy Caucasian and Japanese Male and Female Subjects, and to Assess the Effect That Gender May Have on Its Actions in the Body PHASE1 The study aims to investigate the effect of YM150 and to compare gender and...
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FOCUS Clinical Drug Development GmbH
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YM150 for Prevention of Venous Thromboembolism in Patients With Acute Medical Illness PHASE3 To evaluate the safety and efficacy of the oral dose of YM150 for preventio...
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To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban) PHASE1 The primary objective of this study is to determine the effect of ketoconaz...
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