Found 9 matching trials
YF476 in Barrett's Esophagus
PHASE2A phase 2, randomised, double-blind, out-patient trial to determine if YF47...
Location
Columbia University, Division of Digestive & Liver Diseases
Effect of Repeated Doses of YF476 on Stomach Acidity
PHASE1The objectives of the study were:
1. To show that a single dose of YF476 b...
Location
Hammersmith Medicines Research
Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus
PHASE2The purpose of this study is to determine whether treatment with an experim...
Location
New York Presbyterian Hospital - Columbia
Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers
PHASE1The objective of the study was to assess whether the tolerance to the effec...
Location
Hammersmith Medicines Research
Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States
PHASE1The objectives of the study were:
* To compare a single dose of YF476 at 3...
Location
Hammersmith Medicines Research
Effect of Netazepide on Omeprazole-induced Changes in Chromogranin A and Gastrin
PHASE1Hypergastrinaemia induced by proton pump inhibitor (PPI) treatment is repor...
Location
Multiple Locations
Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers
PHASE1The objectives of this study were:
To compare repeated doses of YF476 at 2...
Location
Hammersmith Medicines Research
Effect of Single Doses of YF476 on Stomach Acidity
PHASE1The objective of the study was to assess the effect of a range of single or...
Location
Hammersmith Medicines Research
Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men
PHASE1The objectives of the study were:
* To assess the safety, tolerability and...
Location
Hammersmith Medicines Research