Found 9 matching trials
Efficacy, Safety and Tolerability of XBD173 in Patients With Generalized Anxiety Disorder
PHASE2This study will test the efficacy, safety and tolerability of XBD173 in the...
Location
Investigational Site
TSPO Modulation in AD
PHASE2The aim of this study is to determine whether pharmacological modulation of...
Status
Enrolling By Invitation
Location
NIHR Imperial CRF
Targeting 18kDa Translocator Protein (TSPO) to Improve Brain Endothelial Cell Function in Cerebral Small Vessel Disease
NAIn healthy people, blood flow to particular areas in the brain increases wh...
Location
Imperial Clinical Research Facility
Endothelial Cell Activation and Total Pulmonary Resistance in PAH
NATo determine whether changes in endothelial cell dysfunction are associated...
Location
Multiple Locations
TSPO Endothelial - EMPATHY
PHASE1The aim of the study is to investigate whether the cells which line the blo...
Status
Enrolling By Invitation
Location
NIHR Imperial CRF
TSPO Occupancy in the Human Lung
NAThe investigators would like to explore the role of TSPO in PAH using a pha...
Status
Enrolling By Invitation
Location
NIHR Imperial CRF
Reproducibility of the 11C-PBR28 PET Signal
NAThe Translocator Protein (TSPO) is a protein which reaches very high levels...
Location
NIHR/Wellcome Trust Imperial Clinical Research Facility
Role of a Mitochondrial Receptor in Blood Sugar Regulation
PHASE2The goal of this clinical trial is to learn whether a single dose of XBD173...
Location
NIHR Trust Imperial Clinical Research Facility
Validation of the 18 kiloDalton Translocator Protein (TSPO) as a Novel Neuroimmunodulatory Target
NAIn multiple sclerosis (MS) cells of the immune system attack the brain caus...
Location
Imperial College Healthcare NHS Trust