Found 31 matching trials
Voxelotor for Improving Oxygen Saturation in Adults
PHASE2The purpose of the study is to evaluate the efficacy of voxelotor for incre...
Location
Duke University Health System
Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE)
PHASE3A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study ...
Location
Multiple Locations
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease
PHASE3This study is a Phase 3, randomized, double-blind, placebo-controlled study...
Location
Children's National Medical Center
Retrospective Real World Oxbryta® Data Collection and Analysis Study
N/AThe aim of this study is to collect and analyze retrospective data on Oxbry...
Location
University of Connecticut Health
Study to Evaluate the Effect of GBT440 Administered to Subjects With IPF on Supplemental Oxygen at Rest
PHASE2This is an open label study in which eligible IPF subjects who are using su...
Location
Multiple Locations
Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease
PHASE2This study consists of four parts, Parts A, B, C, and D.
* Part A is a sin...
Location
Brentwood Clinic UCSF Benioff Children's Hospital Oakland
Study to Evaluate Effects of Investigational Drug on Oxygenation in Healthy Volunteers Under Hypoxic Conditions
PHASE1To evaluate the effect of GBT440 on oxygen saturation at rest and exercise,...
A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease
PHASE1This study is a single center, prospective exploratory pilot study of Sickl...
Location
University of Illinois
Voxelotor Brain Oxygenation and Neurocognitive Study
PHASE4This is an open label, single arm multicenter trial to evaluate the effect ...
Location
Washington University School of Medicine
A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease
PHASE1The purpose of this study is to assess the safety, tolerability, pharmacoki...