Found 34 matching trials
A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanoma PHASE1 This is an open-label, multicenter, Phase Ib, dose-escalation and cohort-ex...
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A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study PHASE3 This is an open-label, multicenter, extension study. Patients who are recei...
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Active Not Recruiting
Location
University of Colorado Cancer Center
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The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs PHASE2 This is a prospective non-randomized national clinical phase 2 trial that a...
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Turku University Hospital Cancer Centre
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Neoadjuvant Vemurafenib + Cobimetinib + Atezolizumab in Melanoma: NEO-VC PHASE2 Evaluation of the efficacy, safety and biologic effects of neo-adjuvant tre...
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Department of Dermatology & Skin Cancer University Hospital La Timone, Aix-Marseille University
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Improving Public Cancer Care by Implementing Precision Medicine in Norway PHASE2 IMPRESS-Norway is a prospective, non-randomized clinical trial evaluating e...
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Sykehuset Ålesund
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Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis PHASE2 The purpose of this study is to determine wether cobimetinib + vemurafenib ...
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SMMART Adaptive Clinical Treatment (ACT) Trial EARLY_PHASE1 SMMART-ACT is a feasibility pilot study to determine if testing samples fro...
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Multiple Locations
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Trial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant Melanoma PHASE3 This trial explores the immunologic effects of vemurafenib (BRAF inhibitor)...
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The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy PHASE2 Rationale:
The combination of ipilimumab and nivolumab induces relatively ...
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The Netherlands Cancer Institute
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Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain Metastases PHASE2 The purpose of this study is to evaluate the effectiveness of the combinati...
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