Found 6 matching trials
A Study to Evaluate Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Adults With Cystic Fibrosis PHASE1 Evaluate the safety and tolerability of VX-659 in healthy subjects...
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Multiple Locations
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A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis PHASE2 This is a Phase 2, randomized, double-blind, placebo- and tezacaftor/ivacaf...
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Yale New Haven Hospital
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A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy PHASE3 This study will evaluate the long-term safety and tolerability of VX-659 in...
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University of Alabama at Birmingham
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Evaluation of VX-659/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age PHASE3 This study will evaluate the pharmacokinetics (PK), safety, tolerability, e...
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Children's Hospital Colorado
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A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) PHASE3 This study will evaluate the efficacy of VX-659 in triple combination (TC) ...
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University of Alabama at Birmingham
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A Study of VX-659 Combination Therapy in CF Subjects Homozygous for F508del (F/F) PHASE3 This study will evaluate the efficacy of VX-659 in triple combination (TC) ...
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University of Alabama at Birmingham
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