Found 16 matching trials
A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis PHASE2 This is a Phase 2, randomized, double-blind, placebo- and tezacaftor/ivacaf...
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Yale New Haven Hospital
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Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age PHASE3 The purpose of this study is to evaluate the pharmacokinetics, safety, tole...
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Active Not Recruiting
Location
Children's Hospital of Orange County
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Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants PHASE1 The purpose of this study is to evaluate the effect of multiple doses of va...
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Altasciences - Kansas City
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Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations PHASE2 This study will evaluate the efficacy and safety of CTP-656 in patients wit...
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University of Southern California
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A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA) PHASE1 The purpose of this study is to evaluate the relative bioavailability, food...
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Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment PHASE1 The purpose of this study is to evaluate the pharmacokinetics (PK) and safe...
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Clinical Pharmacology of Miami, LLC
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A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis PHASE2 The purpose of this study is to evaluate the efficacy, safety, pharmacodyna...
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University of Alabama at Birmingham
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A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy PHASE3 The purpose of this study is to evaluate the long-term safety, tolerability...
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Active Not Recruiting
Location
University of Alabama at Birmingham
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A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor PHASE1 The purpose of this study is to evaluate the relative bioavailability of a ...
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ICON Salt Lake City
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Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis PHASE1 The purpose of the study is to evaluate safety, tolerability, and pharmacok...
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Joe DiMaggio Cycstic Fibrosis & Pulmonary Center
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